منابع مشابه
Placental and fetal manifestations of cytomegalovirus infection.
Five cases of fetal cytomegalovirus infection are presented to illustrate the nature of the placental disease and the difference in fetal infectious sequelae. Widespread fetal infection occurred in very early dissemination of the virus with little inflammatory participation, In later stages both placental and fetal tissues sponsor an intense inflammatory infiltration with numerous plasma cells,...
متن کاملCytomegalovirus Infection and Atherosclerosis: A Systematic Review
Cytomegalovirus (CMV) infection is one of the most common infections that affects humans’ cardiovascular system. Although the literature includes controversial evidence for any correlation between CMV infection and arterial atherosclerosis, the majority of studies, especially those with larger patient population and stronger data stand for such a relationship. However, the number of prospective...
متن کاملPlacental extravillous cytotrophoblasts persistently express class I major histocompatibility complex molecules after human cytomegalovirus infection.
Human cytomegalovirus (HCMV) downregulates the class I major histocompatibility complexes (MHCs), HLA-A and -B, in infected fibroblasts to escape from antigen-specific cytotoxic T lymphocytes. The HCMV genes responsible for the downregulation of MHCs are US2, US3, US6, and US11, which encode type I membrane proteins working at the endoplasmic reticulum (ER). However, it is largely unknown wheth...
متن کاملHuman cytomegalovirus infection of placental cytotrophoblasts in vitro and in utero: implications for transmission and pathogenesis.
Human cytomegalovirus (CMV) is the leading cause of prenatal viral infection. Affected infants may suffer intrauterine growth retardation and serious neurologic impairment. Analysis of spontaneously aborted conceptuses shows that CMV infects the placenta before the embryo or fetus. In the human hemochorial placenta, maternal blood directly contacts syncytiotrophoblasts that cover chorionic vill...
متن کاملPlacental enlargement in women with primary maternal cytomegalovirus infection is associated with fetal and neonatal disease.
BACKGROUND Serological testing for primary maternal cytomegalovirus (CMV) infection during pregnancy is not routine, but ultrasound studies are routine. Therefore, we evaluated placental thickening in women with primary CMV infection during pregnancy. METHODS The study included 92 women with primary CMV infection during pregnancy and 73 CMV-seropositive pregnant women without primary CMV infe...
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ژورنال
عنوان ژورنال: Archives of Pathology & Laboratory Medicine
سال: 2018
ISSN: 0003-9985,1543-2165
DOI: 10.5858/arpa.2017-0421-rs